diff --git a/src/coreclr/jit/codegenarm64.cpp b/src/coreclr/jit/codegenarm64.cpp
index b1dfa28f51720f..85bebf191cc2ec 100644
--- a/src/coreclr/jit/codegenarm64.cpp
+++ b/src/coreclr/jit/codegenarm64.cpp
@@ -2196,7 +2196,9 @@ void CodeGen::instGen_Set_Reg_To_Imm(emitAttr       size,
     }
     else
     {
-        if (emitter::emitIns_valid_imm_for_mov(imm, size))
+        emitAttr immSize = EA_SIZE(size);
+
+        if (emitter::emitIns_valid_imm_for_mov(imm, immSize))
         {
             GetEmitter()->emitIns_R_I(INS_mov, size, reg, imm, INS_OPTS_NONE,
                                       INS_SCALABLE_OPTS_NONE DEBUGARG(targetHandle) DEBUGARG(gtFlags));
@@ -2214,7 +2216,7 @@ void CodeGen::instGen_Set_Reg_To_Imm(emitAttr       size,
             // Determine whether movn or movz will require the fewest instructions to populate the immediate
             int preferMovn = 0;
 
-            for (int i = (size == EA_8BYTE) ? 48 : 16; i >= 0; i -= 16)
+            for (int i = (immSize == EA_8BYTE) ? 48 : 16; i >= 0; i -= 16)
             {
                 if (uint16_t(imm >> i) == 0xffff)
                     ++preferMovn; // a single movk 0xffff could be skipped if movn was used
@@ -2229,7 +2231,7 @@ void CodeGen::instGen_Set_Reg_To_Imm(emitAttr       size,
             // This can allow skipping filling a halfword
             uint16_t skipVal = (preferMovn > 0) ? 0xffff : 0;
 
-            unsigned bits = (size == EA_8BYTE) ? 64 : 32;
+            unsigned bits = (immSize == EA_8BYTE) ? 64 : 32;
 
             // Iterate over imm examining 16 bits at a time
             for (unsigned i = 0; i < bits; i += 16)
diff --git a/src/tests/JIT/Regression/JitBlue/Runtime_132268/Runtime_132268.cs b/src/tests/JIT/Regression/JitBlue/Runtime_132268/Runtime_132268.cs
new file mode 100644
index 00000000000000..2c2e116d3c7e1e
--- /dev/null
+++ b/src/tests/JIT/Regression/JitBlue/Runtime_132268/Runtime_132268.cs
@@ -0,0 +1,47 @@
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+
+// Regression test for https://github.com/dotnet/runtime/issues/132268
+//
+// Requires an arm64 AOT compilation (crossgen2/NativeAOT) to hit the byref constant path.
+
+using System;
+using System.Runtime.CompilerServices;
+using System.Runtime.InteropServices;
+using Xunit;
+
+namespace Runtime_132268;
+
+public unsafe class Runtime_132268
+{
+    [MethodImpl(MethodImplOptions.AggressiveInlining)]
+    private static ref byte GetNonNullPinnableReference(Span<byte> buffer)
+    {
+        return ref buffer.Length != 0 ? ref MemoryMarshal.GetReference(buffer) : ref Unsafe.AsRef<byte>((void*)1);
+    }
+
+    [MethodImpl(MethodImplOptions.NoInlining)]
+    private static int Consume(byte* p, int length) => p is null ? -1 : length;
+
+    [MethodImpl(MethodImplOptions.AggressiveInlining)]
+    private static int Pin(Span<byte> destination)
+    {
+        fixed (byte* p = &GetNonNullPinnableReference(destination))
+        {
+            int status = Consume(p, destination.Length);
+
+            if (status != 0)
+            {
+                throw new InvalidOperationException();
+            }
+
+            return status;
+        }
+    }
+
+    [Fact]
+    public static void TestEntryPoint()
+    {
+        Assert.Equal(0, Pin(default));
+    }
+}
diff --git a/src/tests/JIT/Regression/Regression_ro_2.csproj b/src/tests/JIT/Regression/Regression_ro_2.csproj
index ecfbfd02be8a71..509acf83e4717a 100644
--- a/src/tests/JIT/Regression/Regression_ro_2.csproj
+++ b/src/tests/JIT/Regression/Regression_ro_2.csproj
@@ -128,6 +128,7 @@
     <Compile Include="JitBlue\GitHub_131472\GitHub_131472.cs" />
     <Compile Include="JitBlue\Runtime_122237\Runtime_122237.cs" />
     <Compile Include="JitBlue\Runtime_131716\Runtime_131716.cs" />
+    <Compile Include="JitBlue\Runtime_132268\Runtime_132268.cs" />
   </ItemGroup>
   <Import Project="$(TestSourceDir)MergedTestRunner.targets" />
 </Project>