diff --git a/CHANGELOG.md b/CHANGELOG.md
index 65a121f9fd7d..1b9081231899 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,7 +7,9 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## [Unreleased]
 
-- Nothing yet!
+### Fixed
+
+- Ensure custom variants using `@scope` wrap the generated utilities instead of nesting inside them ([#20344](https://github.com/tailwindlabs/tailwindcss/pull/20344))
 
 ## [4.3.3] - 2026-07-16
 
diff --git a/packages/tailwindcss/src/ast.test.ts b/packages/tailwindcss/src/ast.test.ts
index f3499b350752..d6db07174d37 100644
--- a/packages/tailwindcss/src/ast.test.ts
+++ b/packages/tailwindcss/src/ast.test.ts
@@ -1093,6 +1093,30 @@ describe('optimization', () => {
       `)
     })
 
+    it('should hoist `@scope` at-rules', async () => {
+      expect(
+        optimize(css`
+          @layer utilities {
+            .a {
+              @scope (.b) to (.c) {
+                --x: 1;
+              }
+            }
+          }
+        `),
+      ).toMatchInlineSnapshot(`
+        "
+        @layer utilities {
+          @scope (.b) to (.c) {
+            .a {
+              --x: 1;
+            }
+          }
+        }
+        "
+      `)
+    })
+
     it('should leave `@property` and `@apply` alone', async () => {
       expect(
         optimize(css`
diff --git a/packages/tailwindcss/src/ast.ts b/packages/tailwindcss/src/ast.ts
index e22c13e83900..8777de06e5ba 100644
--- a/packages/tailwindcss/src/ast.ts
+++ b/packages/tailwindcss/src/ast.ts
@@ -1311,6 +1311,7 @@ const HOISTABLE_AT_RULES = new Set([
   '@layer',
   '@media',
   '@page',
+  '@scope',
   '@starting-style',
   '@supports',
   '@view-transition',
@@ -1323,6 +1324,7 @@ const DROPPABLE_IF_EMPTY_AT_RULES = new Set([
   '@container',
   '@media',
   '@page',
+  '@scope',
   '@starting-style',
   '@supports',
   '@view-transition',
diff --git a/packages/tailwindcss/src/index.test.ts b/packages/tailwindcss/src/index.test.ts
index 2a72336fb738..fe76d39075d1 100644
--- a/packages/tailwindcss/src/index.test.ts
+++ b/packages/tailwindcss/src/index.test.ts
@@ -4683,6 +4683,64 @@ describe('@custom-variant', () => {
         "
       `)
     })
+
+    test('@scope with @slot', async () => {
+      expect(
+        await run(
+          ['in-checkout:underline'],
+          css`
+            @custom-variant in-checkout {
+              @scope (.checkout) {
+                @slot;
+              }
+            }
+
+            @layer utilities {
+              @tailwind utilities;
+            }
+          `,
+        ),
+      ).toMatchInlineSnapshot(`
+        "
+        @layer utilities {
+          @scope (.checkout) {
+            .in-checkout\\:underline {
+              text-decoration-line: underline;
+            }
+          }
+        }
+        "
+      `)
+    })
+
+    test('@scope with a limit with @slot', async () => {
+      expect(
+        await run(
+          ['in-checkout:underline'],
+          css`
+            @custom-variant in-checkout {
+              @scope (.checkout) to (.payment) {
+                @slot;
+              }
+            }
+
+            @layer utilities {
+              @tailwind utilities;
+            }
+          `,
+        ),
+      ).toMatchInlineSnapshot(`
+        "
+        @layer utilities {
+          @scope (.checkout) to (.payment) {
+            .in-checkout\\:underline {
+              text-decoration-line: underline;
+            }
+          }
+        }
+        "
+      `)
+    })
   })
 
   test('built-in variants can be overridden while keeping their order', async () => {